Relfydess Botulinum Toxin:
Next-Generation Anti-Wrinkle Treatment
available at Needle Nurse Aesthetics
Relfydess® (RelabotulinumtoxinA) is the latest advancement in neuromodulator aesthetics — a ready-to-use, liquid botulinum toxin type A injectable that smooths dynamic facial lines while maintaining natural expression. Unlike traditional powdered formulations that need reconstitution, Relfydess arrives pre-mixed for precision dosing and consistent results.
Learn more from the manufacturer: GLADERMA
Why Relfydess is a Game-Changer in Aesthetics
Ready-to-Use Liquid Formulation
Relfydess doesn’t require mixing before treatment. This liquid format supports precise dosing and consistent delivery every time, reducing preparation errors common with traditional powders.
Fast Onset of Results
Many patients begin to notice visible softening of lines within 1–3 days, faster than many traditional botulinum toxins. Some clinical data indicate effects from Day 1 for up to ~39% of patients.
Long-Lasting Smoothness
Clinical trials report that up to 75% of patients maintain improvements for up to 6 months following treatment. This extended duration means fewer appointments and more time enjoying results
Natural-Looking Movement
Relfydess is designed to smooth dynamic wrinkles — such as frown lines and crow’s feet — while preserving expressive, natural facial movement, avoiding the ‘frozen’ look some patients fear.
Highly Purified, Protein-Free
Created using PEARL™ Technology, Relfydess is free from complexing proteins and animal-derived components. This purity may help minimise immunogenic response and supports predictable performance.
Simplified Volumetric Dosing
Because it’s pre-diluted, practitioners can apply volumetric dosing with minimal variability, ensuring treatment accuracy and reducing product waste.
Treatment Areas & Ideal Candidates
Relfydess is typically used for aesthetic smoothing of:
✔ Frown lines (glabellar lines)
✔ Crow’s feet (lateral canthal lines)
✔ Horizontal forehead lines (in selected cases)
It’s most suitable for adults under 65 with moderate to severe dynamic wrinkles who want natural, expressive results with longer intervals between treatments.
How Relfydess Works
Relfydess temporarily relaxes the facial muscles responsible for repetitive contraction and expression lines. When these muscles move less forcefully, the overlying skin creases less, which smooths the appearance of lines over time.
Quick Procedure Overview
Duration: 10–15 minutes
Downtime: Minimal — most patients return to daily activities immediately
Onset: Visible changes within 24–72 hours
Duration: Results can last up to 6 months
Patients may experience minor redness, swelling or tenderness at injection sites that typically resolve within a few hours. As with all neuromodulators, individual results vary.
Relfydess vs Traditional Botulinum Toxin
| Feature | Relfydess | Traditional |
|---|---|---|
| Formulation | Ready-to-use liquid | Powder requiring reconstitution |
| Onset of action | Often 1–3 days | Typically 3–5+ days |
| Duration | Up to ~6 months | ~3–4 months |
| Complexing proteins | No | Includes proteins in some brands |
| Dosing precision | Highly consistent | Dependent on reconstitution |
Manufacturer Information & Links
Galderma is a global dermatology leader with a broad portfolio of aesthetic injectables, including Relfydess and the Restylane® range.
Is Relfydess Right for You?
Relfydess can be ideal if you:
• Want a modern neuromodulator with fast-acting results
• Prefer natural facial expression post-treatment
• Desire longer intervals between appointments
• Value precision and consistency in dosing
However, it’s a prescription-only treatment that must be administered by a qualified aesthetic clinician. A consultation will be needed to determine if Relfydess suits your goals, medical history, and facial anatomy.